What we know about mRNA vaccines

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By Apoorva Mandavilli, Christina Thornell, Laura Bult and James SurdamMarch 11, 2025

On the five-year anniversary of the Covid pandemic, a Times reporter, Apoorva Mandavilli, looks back at the success of, and the backlash to, the mRNA vaccine. There’s no question that this vaccine technology saved millions of lives. But the vaccine couldn’t provide total protection against transmission or infection, and there were rare cases of side effects, leading to confusion among the American public.

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