Publisher Health

In a small study, patients with the syndrome were more likely to experience reactivation of Epstein-Barr virus and high levels of a coronavirus protein.The Covid-19 vaccines were powerfully protective, preventing millions of deaths. But in a small number of people, the shots may have led to a constellation of side effects that includes fatigue, exercise intolerance, brain fog, tinnitus and dizziness, together referred to as “post-vaccination syndrome,” according to a small new study.Some people with this syndrome appear to show distinct biological changes, the research found — among them differences in immune cells, reawakening of a dormant virus called Epstein-Barr, and the persistence of a coronavirus protein in their blood.The study was posted online Wednesday and has not yet been published in a scientific journal. “I want to emphasize that this is still a work in progress,” said Akiko Iwasaki, an immunologist at Yale University who led the work.“It’s not like this study determined what’s making people sick,” she said, “but it’s the first kind of glimpse at what may be going on within these people.”Independent experts noted that the findings were not conclusive on their own. Yet the results, from a scientific team known for rigorous work, suggest that post-vaccination syndrome deserves further scrutiny, they said.“One of the most important things is that we get some attention to really shine a light on this and try to understand exactly what it is,” said John Wherry, director of the Institute for Immunology at the University of Pennsylvania. (Dr. Wherry has previously collaborated with Dr. Iwasaki’s team, but did not participate in this work.)We are having trouble retrieving the article content.Please enable JavaScript in your browser settings.Thank you for your patience while we verify access. If you are in Reader mode please exit and log into your Times account, or subscribe for all of The Times.Thank you for your patience while we verify access.Already a subscriber? Log in.Want all of The Times? Subscribe.

The Human Virome Program will analyze samples from thousands of volunteers in an effort to understand how viruses affect health.The viruses we know best are the ones that make us sick — the influenza viruses that send us to bed and the smallpox viruses that may send us to the grave.But healthy people are rife with viruses that don’t make us ill. Scientists estimate that tens of trillions of viruses live inside of us, though they’ve identified just a fraction of them. A vast majority are benign, and some may even be beneficial. We don’t know for sure, because most of the so-called human virome remains a mystery.This year, five universities are teaming up for an unprecedented hunt to identify these viruses. They will gather saliva, stool, blood, milk and other samples from thousands of volunteers. The five-year effort, called the Human Virome Program and supported by $171 million in federal funding, will inspect the samples with artificial intelligence systems, hoping to learn about how the human virome influences our health.“I think it will swamp the data that we’ve had up until now,” said Frederic Bushman, a microbiologist at the University of Pennsylvania and one of the program’s leaders.The first hints of the human virome emerged over a century ago. Analyzing stool samples, scientists discovered viruses known as phages that could infect bacteria inside the gut. Phages also turned up in the mouth, lungs and skin.Scientists later found viruses that infected our own cells without causing any major symptoms. A vast majority of the world’s population gets infected with cytomegaloviruses, for example, which can colonize just about every organ.We are having trouble retrieving the article content.Please enable JavaScript in your browser settings.Thank you for your patience while we verify access. If you are in Reader mode please exit and log into your Times account, or subscribe for all of The Times.Thank you for your patience while we verify access.Already a subscriber? Log in.Want all of The Times? Subscribe.

Max’s unusually accurate medical drama, starring Noah Wyle as a beleaguered E.R. physician, has become the talk of real-life hospital breakrooms.Doctors and nurses who love Max’s “The Pitt” remember the moment they realized it wasn’t like other medical shows.Caitlin Dwyer, a charge nurse in Milwaukee, took note of a character’s decision — counterintuitive but medically correct — not to defibrillate a patient with no pulse.Dr. Elizabeth Rempfer, an attending physician in Maryland, felt a pang of recognition at the depiction of a chaotic and desperate waiting room.For Dr. Tricia Pendergrast, a resident physician in Ann Arbor, Mich., it was a character who faced such an unrelenting caseload that even a trip to the bathroom was cut short.“It’s the first time that I’ve watched doctors on television that I felt like I could see myself in them,” she said.Most medical professionals learned long ago not to expect reality in dramatizations of their work. From the early days of “General Hospital,” to “Grey’s Anatomy” and its various spinoffs, to more recent hits like “The Good Doctor” and “Brilliant Minds,” TV medical dramas have tended to go heavy on the drama, light on the medicine.We are having trouble retrieving the article content.Please enable JavaScript in your browser settings.Thank you for your patience while we verify access. If you are in Reader mode please exit and log into your Times account, or subscribe for all of The Times.Thank you for your patience while we verify access.Already a subscriber? Log in.Want all of The Times? Subscribe.

The condition, which entails pneumonia in both lungs, is potentially grave, according to health experts.Pope Francis, who remains hospitalized, has bilateral pneumonia, the Vatican said on Tuesday.The term simply means pneumonia in both lungs, said Dr. James Musser, director of the center for infectious diseases at the Houston Methodist Research Institute. He added that, without examining a patient, he could not say anything specific about his condition.In general, pneumonia is an infection of the small airways of the lungs. As the body mounts an inflammatory response, small pockets in the lungs fill with immune cells; symptoms can include fever, cough and shaking chills. To diagnose the illness, a doctor typically asks the patient to say a long “e,” as if the person were singing. Through a stethoscope, the “e” of a pneumonia patient sounds like an “a,” said Dr. Paul Pottinger, a professor of infectious diseases at the University of Washington.Most people with pneumonia recover well at home and do not need to be hospitalized. But for older people, pneumonia can be “a deadly situation,” infectious disease experts said.Dr. Peter Chin-Hong, professor of medicine and infectious diseases at the University of California, San Francisco, added that “the mortality rate goes up after age 85.” The pope is 88.The most likely cause of pneumonia is an infection caused by a bacterium, Streptococcus pneumoniae, according to Dr. Chin-Hong. “The No. 1, 2 and 3 cause of pneumonia is strep pneumonia,” he said.The illness can respond to antibiotics, but bacteria can sometimes spill out of the lungs and into the rest of the body, resulting in sepsis, a dangerous situation. A vaccine can help mitigate this sepsis risk but does not prevent the condition, Dr. Chin-Hong said.Dr. Pottinger noted that, although strep pneumonia can involve both lungs, it usually is confined to one lobe of one lung. Most bilateral pneumonia, he said, is caused by viruses, including influenza, or other bacteria. Other causes include respiratory syncytial virus, or R.S.V., Legionella, mycoplasma and chlamydia, Dr. Pottinger said.He agreed with Dr. Chin-Hong about the likely gravity of the pope’s condition.“It is a very scary situation,” Dr. Pottinger said.

14 minutes agoNick TriggleGetty ImagesSenior doctors responsible for monitoring cancer care in England and Wales are concerned failings in NHS services are contributing to up to half of patients are not getting the right treatment for some cancers.

7 hours agoNia PriceBBC News

Jim Jones, the director of the Food and Drug Administration’s food division, resigned on Monday, citing what he called “indiscriminate” layoffs that would make it “fruitless for him to continue.”In his resignation letter, Mr. Jones estimated that 89 people of the 2,000 in his division were fired over the weekend, many of them freshly hired to do more in-depth work on chemical safety to protect the nation’s food supply.“I was looking forward to working to pursue the department’s agenda of improving the health of Americans by reducing diet-related chronic disease and risks from chemicals in food,” Mr. Jones wrote in the letter submitted to Sara Brenner, the acting commissioner of the F.D.A.But the Trump administration’s “disdain for the very people” who would do that work gave him no choice but to depart, he said.Mr. Jones also singled out Robert F. Kennedy Jr., the newly appointed secretary of the Department of Health and Human Services, for criticizing the F.D.A. as being too beholden to the industries it oversees and for vowing to to dismiss the agency’s nutrition staff.“The secretary’s comments impugning the integrity of the food staff, asserting they are corrupt based on falsities, is a disservice to everyone,” Mr. Jones wrote in the letter.We are having trouble retrieving the article content.Please enable JavaScript in your browser settings.Thank you for your patience while we verify access. If you are in Reader mode please exit and log into your Times account, or subscribe for all of The Times.Thank you for your patience while we verify access.Already a subscriber? Log in.Want all of The Times? Subscribe.

A core group of so-called disease detectives, who track outbreaks, was apparently spared. But other young researchers are out of jobs.The notices came all weekend, landing in the inboxes of federal scientists, doctors and public health professionals: Your work is no longer needed.At the National Institutes of Health, the nation’s premier biomedical research agency, an estimated 1,200 employees — including promising young investigators slated for larger roles — have been dismissed.At the Centers for Disease Control and Prevention, two prestigious training programs were gutted: one that embeds recent public health graduates in local health departments and another to cultivate the next generation of Ph.D. laboratory scientists. But the agency’s Epidemic Intelligence Service — the “disease detectives” who track outbreaks around the world — has apparently been spared, perhaps because of an uproar among alumni after a majority of its members were told on Friday that they would be let go.President Trump’s plan to shrink the size of the federal work force dealt blows to thousands of civil servants in the past few days. But the cuts to the Department of Health and Human Services — coming on the heels of the coronavirus pandemic, the worst public health crisis in a century — have been especially jarring. Experts say the firings threaten to leave the country exposed to further shortages of health workers, putting Americans at risk if another crisis erupts.Public health officials, for instance, have been tracking a lethal strain of bird flu that they say remains a low risk to Americans. In recent weeks, however, it claimed its first victim in the United States — a patient in Louisiana who had been exposed to a backyard flock.“It’s not canceled,” Elon Musk, the billionaire in charge of the downsizing, wrote on social media in response to the blowback about the purported dismantling of the Epidemic Intelligence Service.We are having trouble retrieving the article content.Please enable JavaScript in your browser settings.Thank you for your patience while we verify access. If you are in Reader mode please exit and log into your Times account, or subscribe for all of The Times.Thank you for your patience while we verify access.Already a subscriber? Log in.Want all of The Times? Subscribe.

Oxygen is vital to many medical procedures. But a safe, affordable supply is severely lacking around the world, according to a new report.At the height of the Covid-19 pandemic, millions of people in poor nations died literally gasping for breath, even in hospitals. What they lacked was medical oxygen, which is in short supply in much of the world.On Monday, a panel of experts published a comprehensive report on the shortage. Each year, the report noted, more than 370 million people worldwide need oxygen as part of their medical care, but fewer than 1 in 3 receive it, jeopardizing the health and lives of those who do not. Access to safe and affordable medical oxygen is especially limited in low- and middle-income nations.“The need is very urgent,” said Dr. Hamish Graham, a pediatrician and a lead author of the report. “We know that there’s more epidemics coming, and there’ll be another pandemic, probably like Covid, within the next 15 to 20 years.”The report, published in The Lancet Global Health, comes just weeks after the Trump administration froze foreign aid programs, including some that could improve access to oxygen.Boosting the availability of medical oxygen would require an investment of about $6.8 billion, the report noted. “Within the current climate, that’s obviously going to become a bit more of a challenge,” said Carina King, an infectious disease epidemiologist at the Karolinska Institute and a lead author of the report.Still, she said, governments and funding organizations should prioritize medical oxygen because of its importance across health care. People of all ages may need oxygen for pneumonia and other respiratory conditions, for severe infections including malaria and sepsis, for surgeries and for chronic lung conditions.We are having trouble retrieving the article content.Please enable JavaScript in your browser settings.Thank you for your patience while we verify access. If you are in Reader mode please exit and log into your Times account, or subscribe for all of The Times.Thank you for your patience while we verify access.Already a subscriber? Log in.Want all of The Times? Subscribe.

4 hours agoLola MayorBBC Wales News