Pregnancy-related mortality has risen sharply, and doctors have overlooked a particularly dangerous period: from six weeks to one year after the birth.During a recent five-year period, a substantial portion of maternal deaths in America — almost one-third — took place more than six weeks after childbirth, at a time when most new mothers think they are in the clear, researchers reported on Wednesday.The study, published in JAMA Network Open, is one of the first to track maternal health complications during pregnancy and in the year after delivery.Pregnancy-related death rates in the United States rose almost 28 percent from 2018 to 2022, the researchers found, surging at the height of the Covid-19 pandemic in 2021 before subsiding somewhat.“Our study illustrates why we can’t take our eyes off maternal health,” said Dr. Rose L. Molina, an associate professor of obstetrics, gynecology and reproductive biology at Harvard Medical School and one of the study’s authors.Women need “access to high-quality care from the moment of conception to a full year after birth,” she added. While there has been a growing emphasis on care in the year after childbirth, “we’re not there yet.”The study was based on data from the Centers for Disease Control and Prevention’s division of reproductive health, which monitors maternal mortality and identified the risk of so-called later maternal deaths — those that occur from six weeks to one year after the birth.We are having trouble retrieving the article content.Please enable JavaScript in your browser settings.Thank you for your patience while we verify access. If you are in Reader mode please exit and log into your Times account, or subscribe for all of The Times.Thank you for your patience while we verify access.Already a subscriber? Log in.Want all of The Times? Subscribe.

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The human brain is so complex that scientific brains have a hard time making sense of it. A piece of neural tissue the size of a grain of sand might be packed with hundreds of thousands of cells linked together by miles of wiring. In 1979, Francis Crick, the Nobel-prize-winning scientist, concluded that the anatomy and activity in just a cubic millimeter of brain matter would forever exceed our understanding.“It is no use asking for the impossible,” Dr. Crick wrote.Forty-six years later, a team of more than 100 scientists has achieved that impossible, by recording the cellular activity and mapping the structure in a cubic millimeter of a mouse’s brain — less than one percent of its full volume. In accomplishing this feat, they amassed 1.6 petabytes of data — the equivalent of 22 years of nonstop high-definition video.“This is a milestone,” said Davi Bock, a neuroscientist at the University of Vermont who was not involved in the study, which was published Wednesday in the journal Nature. Dr. Bock said that the advances that made it possible to chart a cubic millimeter of brain boded well for a new goal: mapping the wiring of the entire brain of a mouse.“It’s totally doable, and I think it’s worth doing,” he said.More than 130 years have passed since the Spanish neuroscientist Santiago Ramón y Cajal first spied individual neurons under a microscope, making out their peculiar branched shapes. Later generations of scientists worked out many of the details of how a neuron sends a spike of voltage down a long arm, called an axon. Each axon makes contact with tiny branches, or dendrites, of neighboring neurons. Some neurons excite their neighbors into firing voltage spikes of their own. Some quiet other neurons.Human thought somehow emerges from this mix of excitation and inhibition. But how that happens has remained a tremendous mystery, largely because scientists have been able to study only a few neurons at a time.One type of cell mapped by the scientists, called a Martinotti cell, sends out inhibitory signals that dampen the activity of other neurons in the brain.We are having trouble retrieving the article content.Please enable JavaScript in your browser settings.Thank you for your patience while we verify access. If you are in Reader mode please exit and log into your Times account, or subscribe for all of The Times.Thank you for your patience while we verify access.Already a subscriber? Log in.Want all of The Times? Subscribe.

US President Donald Trump says he will soon announce “major” tariffs on imported pharmaceuticals, a move that could end decades of low-cost global trade in medicines.

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At the very moment that Health Secretary Robert F. Kennedy Jr. was set to take the stage, the governor of Gila River Indian Community was still standing at the podium, articulating his uneasiness around recent Trump administration moves.“Let me repeat that: We have spent a good part of this year providing education on why tribes have a political status that is not D.E.I.,” Gov. Stephen Roe Lewis said to a room of 1,200 people, who clapped and cheered.When it comes to cuts sought by what has been called the Department of Government Efficiency, “we need a scalpel and not a chain saw approach to making these changes,” he said. The Gila River Wild Horse Pass Resort and Casino in Chandler, Ariz., owned and operated by two tribes, was the latest stop on Mr. Kennedy’s Make American Healthy Again tour through three Southwestern states. Mr. Kennedy was set to host a “fireside chat” at the Tribal Self Governance Conference, an event celebrating 50 years of tribal sovereignty under the Indian Self-Determination and Education Assistance Act.The act, passed by Congress in 1975, marked a shift away from federal government control, so that Native communities could run their own programs based on their unique cultural needs.Mr. Kennedy has long expressed a particular zeal for improving tribal health, citing his family’s long history of advocacy, his childhood trips to American Indian reservations, and parts of his own environmental career.We are having trouble retrieving the article content.Please enable JavaScript in your browser settings.Thank you for your patience while we verify access. If you are in Reader mode please exit and log into your Times account, or subscribe for all of The Times.Thank you for your patience while we verify access.Already a subscriber? Log in.Want all of The Times? Subscribe.

So sharp are partisan divisions these days that it can seem as if people are experiencing entirely different realities. Maybe they actually are, according to Leor Zmigrod, a neuroscientist and political psychologist at Cambridge University. In a new book, “The Ideological Brain: The Radical Science of Flexible Thinking,” Dr. Zmigrod explores the emerging evidence that brain physiology and biology help explain not just why people are prone to ideology but how they perceive and share information.This conversation has been edited for clarity and brevity.What is ideology?It’s a narrative about how the world works and how it should work. This potentially could be the social world or the natural world. But it’s not just a story: It has really rigid prescriptions for how we should think, how we should act, how we should interact with other people. An ideology condemns any deviation from its prescribed rules.You write that rigid thinking can be tempting. Why is that?Ideologies satisfy the need to try to understand the world, to explain it. And they satisfy our need for connection, for community, for just a sense that we belong to something.There’s also a resource question. Exploring the world is really cognitively expensive, and just exploiting known patterns and rules can seem to be the most efficient strategy. Also, many people argue — and many ideologies will try to tell you — that adhering to rules is the only good way to live and to live morally.I actually come at it from a different perspective: Ideologies numb our direct experience of the world. They narrow our capacity to adapt to the world, to understand evidence, to distinguish between credible evidence and not credible evidence. Ideologies are rarely, if ever, good.Q: In the book, you describe research showing that ideological thinkers can be less reliable narrators. Can you explain?We are having trouble retrieving the article content.Please enable JavaScript in your browser settings.Thank you for your patience while we verify access. If you are in Reader mode please exit and log into your Times account, or subscribe for all of The Times.Thank you for your patience while we verify access.Already a subscriber? Log in.Want all of The Times? Subscribe.

The consequences of mother-to-child transmission can be enormous, a new study suggests. But the U.S. has dismissed experts working to solve the problem.The Trump administration has dismissed the few remaining health officials who oversaw care for some of the world’s most vulnerable people: more than 500,000 children and more than 600,000 pregnant women with H.I.V. in low-income countries.Expert teams that managed programs meant to prevent newborns from acquiring H.I.V. from their mothers and to provide treatment for infected children were eliminated last week in the chaotic reorganization of the Health and Human Services Department.Some of the consequences of the dismissals are only now coming to light.While it was known that some staff members devoted to H.I.V. prevention in other countries had been lost, The New York Times has learned that all such experts have now been terminated or are awaiting reassignment at the Centers for Disease Control and Prevention, the State Department and the U.S. Agency for International Development.These maternal health programs are still funded by the President’s Emergency Plan For AIDS Relief, or PEPFAR. But without personnel to manage the initiatives or to disburse the money, it’s not clear how the work will continue.The Health and Human Services Department did not respond to a request for comment.“We hope this is not a sign that treating mothers and children is no longer important in PEPFAR, and that this is a mistake that can be corrected,” said a federal health official who spoke on condition of anonymity for fear of retaliation.The stakes are high. Already in sub-Saharan Africa, a child under 15 dies of AIDS every seven minutes.We are having trouble retrieving the article content.Please enable JavaScript in your browser settings.Thank you for your patience while we verify access. If you are in Reader mode please exit and log into your Times account, or subscribe for all of The Times.Thank you for your patience while we verify access.Already a subscriber? Log in.Want all of The Times? Subscribe.

3 hours ago