We tend to think of scribes as being in the mold of Bartleby the Scrivener, the eponymous Wall Street law clerk in Herman Melville’s 1853 short story. Working “silently, palely, mechanically,” Bartleby is an industrious employee who consumes legal documents “as if long famishing for something to copy” — before he eventually turns into an inscrutable refusenik who is relegated to a desk behind a screen that looks out at a brick wall.In ancient Egypt, scribes were more than dreary papyrus-pushers. By and large, they were dignitaries, ranked above artisans and merchants but below priests and nobles. Their status derived chiefly from their literacy, a skill still in its infancy during the Old Kingdom, 4,200 to 4,700 years ago. Influential families sent their teenage sons to train for entry-level jobs at the royal court, where they performed vital administrative functions, such as drawing up contracts, measuring fields for tax purposes and recording the biennial cattle census. There were few if any female scribes.For all their prestige, the scribes of the third millennium B.C. faced many of the same occupational hazards as the desk jockeys and keyboard warriors of today. A new study in the journal Scientific Reports found that the repetitive tasks carried out by Pharaonic-era scriveners, and the postures that they assumed while scrivening, might have caused degenerative changes in their joints, spines and jaws.Museum and university researchers from the Czech Republic examined the remains of 69 adult male skeletons buried from 2700 to 2180 B.C. in a necropolis in Abusir, a complex of pyramids and tombs a few miles south of Cairo. Thirty of the deceased were presumed to have been scribes, judging by their burial location, inferred social rank, or, in six cases, titles found in their tombs.Two scribes in a relief from the Tomb of Akhethotep in Saqqara, Egypt. Scribes performed vital administrative functions, such as drawing up contracts and measuring fields for tax purposes.Heritage Image Partnership Ltd./AlamyThe skeletons of the scribes were compared with those of 39 non-scribes from the same region and time period. “These 39 individuals belonged to the lower strata of society,” said Veronika Dulikova, an Egyptologist at Charles University in Prague and an author of the new paper. “They were buried in humble, mud-brick tombs with a simple niche instead of an inscribed false door, as in the case of members of the elite.” False doors were believed to act as portals between the afterlife and the living world, allowing the soul of the deceased to freely enter and exit the tomb.We are having trouble retrieving the article content.Please enable JavaScript in your browser settings.Thank you for your patience while we verify access. If you are in Reader mode please exit and log into your Times account, or subscribe for all of The Times.Thank you for your patience while we verify access.Already a subscriber? Log in.Want all of The Times? Subscribe.

The government has announced it will push ahead with compensation payments to infected blood victims.

Sweden’s public health agency has recorded what it says is the first case of a more dangerous type of mpox outside the African continent.

UK health chiefs say they are making plans in case a new type of mpox virus is detected in the country – but they emphasise the risk is low.

The virus is evolving, and the newest version spreads more often through heterosexual populations. But the vaccines should still work.Faced once again with a rapidly spreading epidemic of mpox, the World Health Organization on Wednesday declared a global health emergency. The last time the W.H.O. made that call was in 2022, when the disease was still called monkeypox.Ultimately the outbreak affected nearly 100,000 people worldwide, primarily gay and bisexual men, including more than 32,000 in the United States.The W.H.O.’s decision this time was prompted by an escalating crisis of mpox concentrated in the Democratic Republic of Congo. It recently spread to a dozen other African countries. If it is not contained, the virus again may rampage all over the world, experts warned.“There’s a need for concerted effort by all stakeholders, not only in Africa, but everywhere else,” Dr. Dimie Ogoina, a Nigerian scientist and chair of the W.H.O.’s mpox emergency committee, said on Wednesday.Congo alone has reported 15,600 mpox cases and 537 deaths, most of them among children under 15, indicating that the nature of the disease and its mode of spread may have changed.Here’s what to know.We are having trouble retrieving the article content.Please enable JavaScript in your browser settings.Thank you for your patience while we verify access. If you are in Reader mode please exit and log into your Times account, or subscribe for all of The Times.Thank you for your patience while we verify access.Already a subscriber? Log in.Want all of The Times? Subscribe.

Getty ImagesThe UK Health Security Agency (UKHSA) is warning about a small but significant rise in cases of antibiotic-resistant gonorrhoea.

Many patients thought to be in vegetative or minimally conscious states may be capable of thought, researchers reported.When people suffer severe brain damage — as a result of car crashes, for example, or falls or aneurysms — they may slip into a coma for weeks, their eyes closed, their bodies unresponsive.Some recover, but others enter a mysterious state: eyes open, yet without clear signs of consciousness. Hundreds of thousands of such patients in the United States alone are diagnosed in a vegetative state or as minimally conscious. They may survive for decades without regaining a connection to the outside world.These patients pose an agonizing mystery both for their families and for the medical professionals who care for them. Even if they can’t communicate, might they still be aware?A large study published on Wednesday suggests that a quarter of them are.Teams of neurologists at six research centers asked 241 unresponsive patients to spend several minutes at a time doing complex cognitive tasks, such as imagining themselves playing tennis. Twenty-five percent of them responded with the same patterns of brain activity seen in healthy people, suggesting that they were able to think and at least somewhat aware.Dr. Nicholas Schiff, a neurologist at Weill Cornell Medicine and an author of the study, said the study shows that up to 100,000 patients in the United States alone might have some level of consciousness despite their devastating injuries.The results should lead to more sophisticated exams of people with so-called disorders of consciousness, and to more research into how these patients might communicate with the outside world, he said: “It’s not OK to know this and to do nothing.”We are having trouble retrieving the article content.Please enable JavaScript in your browser settings.Thank you for your patience while we verify access. If you are in Reader mode please exit and log into your Times account, or subscribe for all of The Times.Thank you for your patience while we verify access.Already a subscriber? Log in.Want all of The Times? Subscribe.

Four years ago, Casey Harrell sang his last bedtime nursery rhyme to his daughter.By then, A.L.S. had begun laying waste to Mr. Harrell’s muscles, stealing from him one ritual after another: going on walks with his wife, holding his daughter, turning the pages of a book. “Like a night burglar,” his wife, Levana Saxon, wrote of the disease in a poem.But no theft was as devastating to Mr. Harrell, 46, as the fading of his speech. He had sung his last Whitney Houston song at karaoke. A climate activist, he had delivered his last unassisted Zoom presentation to fellow organizers.Last July, doctors at the University of California, Davis, surgically implanted electrodes in Mr. Harrell’s brain to try to discern what he was trying to say. That made him the latest test subject in a daunting scientific quest, one that has attracted deep-pocketed firms like Elon Musk’s company Neuralink: connecting people’s brains to computers, potentially restoring their lost faculties. Doctors told him that he would be advancing the cause of science, but that he was not likely to reverse his fortunes.Yet the results surpassed expectations, the researchers reported on Wednesday in The New England Journal of Medicine, setting a new bar for implanted speech decoders and illustrating the potential power of such devices for people with speech impairments.“It’s very exciting,” said Dr. Edward Chang, a neurosurgeon at University of California, San Francisco, who was not involved in Mr. Harrell’s case but has developed different speech implants. A device that just years ago “seemed like science fiction,” he said, is now “improving, getting optimized, so quickly.”Mr. Harrell’s team sank into his brain’s outer layer four electrode arrays that looked like tiny beds of nails. That was double the number that had recently been implanted in the speech areas of someone with A.L.S., or amyotrophic lateral sclerosis, in a separate study. Each array’s 64 spikes picked up electric impulses from neurons that fired when Mr. Harrell tried to move his mouth, lips, jaw and tongue to speak.We are having trouble retrieving the article content.Please enable JavaScript in your browser settings.Thank you for your patience while we verify access. If you are in Reader mode please exit and log into your Times account, or subscribe for all of The Times.Thank you for your patience while we verify access.Already a subscriber? Log in.Want all of The Times? Subscribe.

The World Health Organization declared a global health emergency over an outbreak that has spread to more than a dozen African countries.Mpox was declared a global health emergency on Wednesday for the second time in three years, as the World Health Organization urged action on a virus spreading rapidly through more than a dozen African countries.The outbreak is most severe in the Democratic Republic of Congo, which has reported 15,600 mpox cases and 537 deaths, according to the U.N. agency. The mpox epidemic there has already proved more deadly than one in 2022, the last time an emergency was announced.Here is what to know about mpox, which was known as monkeypox before health officials, responding to complaints about the word, recommended its current name in 2022.What is mpox and how is it spread?The mpox virus is endemic to Central and Western Africa. The disease is similar to smallpox but less contagious, and the virus is spread primarily through close contact with infected animals or people, and the consumption of contaminated meat.Mpox can also be spread through sexual contact, and there is a risk of transmission to a fetus.Who is currently being affected?Ninety-six percent of the mpox deaths reported in June were in Congo, a country already assailed by an internal conflict and humanitarian crisis. But the disease has now been identified in 13 countries, including for the first time in the East African nations of Burundi, Kenya, Rwanda and Uganda.There are differences between the outbreaks in various regions and countries, depending on the circumstances in each community, according to Dr. Sylvie Jonckheere, an adviser on emerging infectious diseases for Doctors Without Borders. But they share a common feature, she said: “We do not know how to control this outbreak.”We are having trouble retrieving the article content.Please enable JavaScript in your browser settings.Thank you for your patience while we verify access. If you are in Reader mode please exit and log into your Times account, or subscribe for all of The Times.Thank you for your patience while we verify access.Already a subscriber? Log in.Want all of The Times? Subscribe.

Nottinghamshire PoliceThe critical report into the mental healthcare given to Valdo Calocane – a paranoid schizophrenic who fatally stabbed three people in Nottingham last year – is damning.