Resetting the fight-or-flight response

The activation of Protein Kinase A (PKA) is a critical part in how the body responds to stress and starvation. Using a variety of imaging and biochemical techniques, a team of researchers has revealed how the metabolic cycle that activates PKA resets itself between stressful events.

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How to Have Self-Compassion

Cultivating self-compassion can actually help you cope better with life’s struggles.If a friend is struggling with a big challenge or feels defeated, it’s usually our first instinct to offer words of comfort and understanding. But often it’s not so easy to do this for ourselves.We can be our own harshest critics. Practicing a little self-compassion, though, goes a long way. Research shows that when people go through challenges or stressful situations, those who display more self-compassion are more resilient.“We can say, ‘I made a mistake,’ as opposed to saying, ‘I am a mistake,’” said Kristin Neff, an associate professor of educational psychology at the University of Texas at Austin who has studied self-compassion for more than two decades. “It’s a healthier alternative to self-esteem, because it’s not about judging yourself positively, it’s just about being helpful and kind to yourself.”What is self-compassion?Self-compassion is the process of expressing support, warmth and understanding toward yourself during difficult times — and recognizing that you aren’t alone in your imperfections.It arises from mindfulness, which involves staying focused on the present moment without judgment. Self-compassionate people can identify when they are feeling defeated or inadequate, but avoid becoming lost in those feelings so that they can respond to themselves with kindness instead of ruminating, Dr. Neff said.Being kind to yourself doesn’t mean hosting a pity party. Our suffering is not unique — flaws and failures are part of what make us human. And while we all suffer in different ways, the knowledge that suffering is universal can help prevent feelings of shame or isolation.We are having trouble retrieving the article content.Please enable JavaScript in your browser settings.Thank you for your patience while we verify access. If you are in Reader mode please exit and log into your Times account, or subscribe for all of The Times.Thank you for your patience while we verify access.Already a subscriber? Log in.Want all of The Times? Subscribe.

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Checks on Migrant Children by Homeland Security Agents Stir Fear

Agents are showing up unannounced to interview minors in what the government calls “wellness checks.” Critics see the visits as part of the immigration crackdown.For more than a decade, unaccompanied children fleeing hardship have journeyed north from Central America and crossed the Mexico-U.S. border. Many of them have been allowed to stay in the United States, and the government has spared most of them the full weight of immigration enforcement.Under the Trump administration, more of those children are coming face to face with federal agents.From New York to Hawaii, agents have been showing up unannounced at schools, homes and migrant shelters to interview the children.The Trump administration has called these surprise visits “wellness checks” intended to ensure that the children are enrolled in school and being properly cared for. But the agents conducting the visits are not social workers or child welfare specialists, nor are they labor inspectors or truant officers. Rather, the agents are primarily from Homeland Security Investigations, a specialized unit of Immigration and Customs Enforcement that combats drug and weapons smuggling, cybercrimes and financial crimes.When federal agents looking for children arrived unannounced at two Los Angeles elementary schools last month, they were turned away.“ My very first question starts there,” the superintendent of the Los Angeles Unified School District, Alberto Carvalho, said at a news conference. “What interest should a Homeland Security agent have in a first grader or a second grader? A third grader or a fourth grader, for that matter?”Children who arrive in the United States alone have long faced risks, and as their numbers surged, concerns about their well-being have grown. Most of the minors are living safely with family members, but some have fallen prey to labor traffickers and other exploitation.We are having trouble retrieving the article content.Please enable JavaScript in your browser settings.Thank you for your patience while we verify access. If you are in Reader mode please exit and log into your Times account, or subscribe for all of The Times.Thank you for your patience while we verify access.Already a subscriber? Log in.Want all of The Times? Subscribe.

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Judge Finds Government Acted Illegally in Russian Scientist Case

The judge said a customs officer had acted improperly in stripping Kseniia Petrova, a researcher at Harvard Medical School, of her visa after she failed to declare research samples she was carrying into the country.A federal judge on Wednesday said she would grant bail to Kseniia Petrova, a Russian scientist employed by Harvard University, in an immigration case stemming from Ms. Petrova’s failure to declare scientific samples she was carrying into the country.“There does not seem to be either a factual or legal basis for the immigration officer’s actions” in stripping Ms. Petrova of her visa on Feb. 16, Christina Reiss, chief judge of the U.S. District Court in Vermont, said in a court hearing.She added that “Ms. Petrova’s life and well-being are in peril if she is deported to Russia,” as the government has said it intends to do.While traveling to France on vacation, Ms. Petrova agreed to carry back samples of frog embryos from an affiliate laboratory at the request of her supervisor at Harvard Medical School.When the samples were discovered during an inspection of Ms. Petrova’s baggage at Logan Airport in Boston, the customs official canceled her visa on the spot and started deportation proceedings. She was transferred to an Immigration and Customs Enforcement detention center in Louisiana, where she remained for more than three months.At the end of the hearing on Wednesday, Judge Reiss said that “what happened in this case was extraordinary and novel,” and that if she did not take action in the case “there will be no determination” that Ms. Petrova’s rights had been violated.We are having trouble retrieving the article content.Please enable JavaScript in your browser settings.Thank you for your patience while we verify access. If you are in Reader mode please exit and log into your Times account, or subscribe for all of The Times.Thank you for your patience while we verify access.Already a subscriber? Log in.Want all of The Times? Subscribe.

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Scientists test real-time view of brain’s waste removal

A new device that monitors the waste-removal system of the brain may help to prevent Alzheimer s and other neurological diseases, according to a new study. In the study, participants were asleep when they wore the device: a head cap embedded with electrodes that measures shifts in fluid within brain tissue, the neural activity from sleep to wakefulness and changes in the brain s blood vessels.

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