A 66-year-old man from New Hampshire became the fourth person to receive a pig’s kidney.Surgeons in Boston successfully transplanted the kidney of a genetically modified pig into a 66-year-old man with kidney failure last month, Massachusetts General Hospital announced on Friday.It was the fourth pig kidney transplant in the United States, and the first of three that will be done at Mass General as part of a new clinical trial sanctioned by the Food and Drug Administration. Two of the previous patients died shortly after the procedure, including one who was critically ill before the transplant.More than 100,000 people in the country are on waiting lists for transplant organs, mostly kidneys, but there is an acute shortage of human donor organs. Many people will die while waiting.To help alleviate the shortage, several biotech companies are editing the genes of pigs so that their organs will not be easily rejected by the human body.The new clinical trial, which is using organs produced by the biotech company eGenesis, is one of two studies of genetically engineered animal organs that got a green light from regulators earlier this week. The other, sponsored by United Therapeutics Corporation, will begin later this year with six patients, but that number could eventually rise to 50.The latest transplant recipient, Tim Andrews of Concord, N.H., had his surgery in late January and was well enough to be discharged a week later.We are having trouble retrieving the article content.Please enable JavaScript in your browser settings.Thank you for your patience while we verify access. If you are in Reader mode please exit and log into your Times account, or subscribe for all of The Times.Thank you for your patience while we verify access.Already a subscriber? Log in.Want all of The Times? Subscribe.

6 hours agoMiya ChahalBBC News, Nottingham

15 minutes agoMichelle RobertsDigital health editor, BBC News

The data, which appeared fleetingly online on Wednesday, confirmed transmission in two households. Scientists called on the agency to release the full report.Cats that became infected with bird flu might have spread the virus to humans in the same household and vice versa, according to data that briefly appeared online in a report from the Centers for Disease Control and Prevention but then abruptly vanished. The data appear to have been mistakenly posted but includes crucial information about the risks of bird flu to people and pets.In one household, an infected cat might have spread the virus to another cat and to a human adolescent, according to a copy of the data table obtained by The New York Times. The cat died four days after symptoms began. In a second household, an infected dairy farmworker appears to have been the first to show symptoms, and a cat then became ill two days later and died on the third day.The table was the lone mention of bird flu in a scientific report published on Wednesday that was otherwise devoted to air quality and the Los Angeles County wildfires. The table was not present in an embargoed copy of the paper shared with news media on Tuesday, and is not included in the versions currently available online. The table appeared briefly at around 1 p.m., when the paper was first posted, but it is unclear how or why the error might have occurred.The virus, called H5N1, is primarily adapted to birds, but it has been circulating in dairy cattle since early last year. H5N1 has also infected at least 67 Americans but does not yet have the ability to spread readily among people. Only one American, in Louisiana, has died of an H5N1 infection so far.The report was part of the C.D.C.’s prestigious Morbidity and Mortality Weekly Report, which, until two weeks ago, had regularly published every week since the first installment decades ago. But a communications ban on the agency had held the reports back, until the wildfire report was published on Wednesday.Experts said that the finding that cats might have passed the virus to people was not entirely unexpected. But they were alarmed that the finding had not yet been released to the public.We are having trouble retrieving the article content.Please enable JavaScript in your browser settings.Thank you for your patience while we verify access. If you are in Reader mode please exit and log into your Times account, or subscribe for all of The Times.Thank you for your patience while we verify access.Already a subscriber? Log in.Want all of The Times? Subscribe.

Asanda Zondi received a startling phone call last Thursday, with orders to make her way to a health clinic in Vulindlela, South Africa, where she was participating in a research study that was testing a new device to prevent pregnancy and H.IV. infection.The trial was shutting down, a nurse told her. The device, a silicone ring inserted into her vagina, needed to be removed right away.When Ms. Zondi, 22, arrived at the clinic, she learned why: The U.S. Agency for International Development, which funded the study, had withdrawn financial support and had issued a stop-work order to all organizations around the globe that receive its money. The abrupt move followed an executive order by President Trump freezing all foreign aid for at least 90 days. Since then, the Trump administration has taken steps to dismantle the agency entirely.Ms. Zondi’s trial is one of dozens that have been abruptly frozen, leaving people around the world with experimental drugs and medical products in their bodies, cut off from the researchers who were monitoring them, and generating waves of suspicion and fear.The State Department, which now oversees U.S.A.I.D., replied to a request for comment by directing a reporter to USAID.gov, which no longer contains any information except that all permanent employees have been placed on administrative leave. Secretary of State Marco Rubio has said that the agency is wasteful and advances a liberal agenda that is counter to President Trump’s foreign policy.In interviews, scientists — who are forbidden by the terms of the stop-work order to speak with the news media — described agonizing choices: violate the stop-work orders and continue to care for trial volunteers, or leave them alone to face potential side effects and harm.We are having trouble retrieving the article content.Please enable JavaScript in your browser settings.Thank you for your patience while we verify access. If you are in Reader mode please exit and log into your Times account, or subscribe for all of The Times.Thank you for your patience while we verify access.Already a subscriber? Log in.Want all of The Times? Subscribe.

16 hours agoMichael BuchananBBCTwo couples have told the BBC they went through with abortions after an NHS trust mistakenly told them their unborn babies had serious genetic conditions.

She left the agency because of its delay in approving the morning-after pill for over-the-counter use. Her resignation drew national media attention.Susan F. Wood, a women’s health expert who resigned in protest from the Food and Drug Administration in 2005, accusing the agency of knuckling under to politics by not approving over-the-counter sales of the morning-after pill known as Plan B, died on Jan. 17 at her home in London. She was 66.The cause was glioblastoma multiforme, a brain cancer, said Richard Payne, her husband.Dr. Wood was assistant commissioner for women’s health at the F.D.A. during the presidency of George W. Bush when Plan B, a form of emergency contraception, became a flashpoint in the abortion wars.An F.D.A. advisory panel voted 28-0 in 2003 that the pill was safe for nonprescription use. But senior agency officials disregarded precedent and refused to approve over-the-counter sales.Plan B contains high levels of progestin, a hormone found in ordinary birth control pills, and agency scientists considered it to be a contraceptive. But abortion opponents argued that its use was tantamount to ending pregnancies. They further warned that ready access would lead to promiscuous behavior by teenagers, though no data supported that claim.Dr. Wood and others believed that having emergency contraception available without a prescription would mean fewer unwanted pregnancies and fewer abortions.In August 2005, the F.D.A. commissioner, Lester M. Crawford, announced that the agency could not reach a decision on whether to authorize over-the-counter use of Plan B and did not expect to reach one soon.We are having trouble retrieving the article content.Please enable JavaScript in your browser settings.Thank you for your patience while we verify access. If you are in Reader mode please exit and log into your Times account, or subscribe for all of The Times.Thank you for your patience while we verify access.Already a subscriber? Log in.Want all of The Times? Subscribe.

Two new Canadian studies are the largest to date looking at death rates and psychosis associated with cannabis use disorder.Hospital and emergency room patients diagnosed with cannabis use disorder — defined as an inability to stop using cannabis even when the drug is causing harm — died at almost three times the rate of individuals without the disorder over the next five years, according to a study published on Thursday, the largest on the subject.Patients with cannabis use disorder were 10 times as likely to die by suicide as those in the general population. They were also more likely to die from trauma, drug poisonings and lung cancer. Those numbers suggest that cannabis use disorder is about half as dangerous as opioid addiction and slightly less dangerous than alcohol use disorder, the researchers said.A second report, published on Tuesday, found that more cases of schizophrenia and psychosis in Canada have been linked to cannabis use disorder since the drug was legalized.“Many people think, ‘Oh, cannabis is not harmful — it’s organic, it’s natural; how great,’” said Dr. Laura Bierut, a psychiatrist at Washington University School of Medicine in St. Louis who is an author of an editorial accompanying the study of death risk. But the marijuana sold today is far more potent, and more harmful, than what baby boomers smoked in the 1960s and 1970s, she said.“It is a public health threat just like alcohol,” Dr. Bierut said.Recent research suggests that three in 10 cannabis users will develop cannabis use disorder, defined as being unable to stop using cannabis even though it’s causing serious health and social problems. As with alcohol, many people use marijuana recreationally without adverse effects or addiction.We are having trouble retrieving the article content.Please enable JavaScript in your browser settings.Thank you for your patience while we verify access. If you are in Reader mode please exit and log into your Times account, or subscribe for all of The Times.Thank you for your patience while we verify access.Already a subscriber? Log in.Want all of The Times? Subscribe.

Their new method takes 32 minutes.A colleague approached Ernesto Di Maio, a materials scientist in Naples, Italy, and an expert in plastic foams, with a blunt suggestion: “You should do something cooler.” The colleague had a project in mind, Dr. Di Maio recalled. He wanted a perfectly boiled egg.The task was harder than it might seem, as many home cooks know. The yolk and the egg white, or albumen, have different chemical compositions, which call for different heating temperatures. Dr. Di Maio and his colleagues also welcomed the chance to one-up the Michelin-star chef Carlo Cracco, an egg evangelist who charges $52 for an egg yolk dish at his restaurant in Milan.The scientists devised a way of cooking an egg that requires no special culinary skill or fancy gadgets. It took about 300 eggs, though the researchers “didn’t eat all of them,” said Pellegrino Musto, a polymer expert at the National Research Council of Italy.The researchers said their method, published on Thursday, preserves the distinct textures of the egg as well as its nutritional value.The two parts of the egg require different cooking temperatures because they have different chemical components. “The albumen is mainly composed of water and proteins,” said Emilia Di Lorenzo, a graduate student in Dr. Di Maio’s lab at the University of Naples Federico II who recently published a paper on foaming pizza. “Yolk, on the other hand, is much richer in nutrients.”We are having trouble retrieving the article content.Please enable JavaScript in your browser settings.Thank you for your patience while we verify access. If you are in Reader mode please exit and log into your Times account, or subscribe for all of The Times.Thank you for your patience while we verify access.Already a subscriber? Log in.Want all of The Times? Subscribe.

22 minutes agoGetty ImagesHospitals in England have just had their busiest week of this winter so far.